subject area of

• A 130-kDa protein on endothelial cells binds to amino acids 15-42 of the B beta chain of fibrinogen.  Academic Article
• A differential role for cell shape in neutrophil tethering and rolling on endothelial selectins under flow.  Academic Article
• A new role in hemostasis for the adhesion receptor P-selectin.  Academic Article
• ADAMTS13: a new link between thrombosis and inflammation.  Academic Article
• Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin.  Academic Article
• Acute passive anti-glomerular basement membrane nephritis in P-selectin-deficient mice.  Academic Article
• Angiogenesis in P- and E-selectin-deficient mice.  Academic Article
• Antithrombotic activity of TNF-alpha.  Academic Article
• Blood cell dynamics in P-selectin-deficient mice.  Academic Article
• Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin-deficient mouse.  Academic Article
• Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins.  Academic Article
• Defect in regulated secretion of P-selectin affects leukocyte recruitment in von Willebrand factor-deficient mice.  Academic Article
• Defects in hemostasis in P-selectin-deficient mice.  Academic Article
• Dietary omega-3 alpha-linolenic acid does not prevent venous thrombosis in mice.  Academic Article
• Distinct cell surface ligands mediate T lymphocyte attachment and rolling on P and E selectin under physiological flow.  Academic Article
• Divergent fates of P- and E-selectins after their expression on the plasma membrane.  Academic Article
• Donor MHC and adhesion molecules in transplant arteriosclerosis.  Academic Article
• Elevated levels of homocysteine compromise blood-brain barrier integrity in mice.  Academic Article
• Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis.  Academic Article
• Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow.  Academic Article
• Formation of platelet strings and microthrombi in the presence of ADAMTS-13 inhibitor does not require P-selectin or beta3 integrin.  Academic Article
• Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1.  Academic Article
• Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation.  Academic Article
• Infection-mediated early-onset periodontal disease in P/E-selectin-deficient mice.  Academic Article
• Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling.  Academic Article
• Insights into selectin function from knockout mice.  Academic Article
• Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.  Academic Article
• Interactions of human alpha/beta and gamma/delta T lymphocyte subsets in shear flow with E-selectin and P-selectin.  Academic Article
• Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models.  Academic Article
• Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice.  Academic Article
• Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins.  Academic Article
• Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow.  Academic Article
• Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.  Academic Article
• Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.  Academic Article
• Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18.  Academic Article
• New discoveries with mice mutant in endothelial and platelet selectins.  Academic Article
• Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation.  Academic Article
• P- and E-selectins are required for the leukocyte recruitment, but not the tissue swelling, associated with IgE- and mast cell-dependent inflammation in mouse skin.  Academic Article
• P-Selectin and platelet clearance.  Academic Article
• P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo.  Academic Article
• P-selectin and E-selectin. Distinct but overlapping leukocyte ligand specificities.  Academic Article
• P-selectin and leukocyte microparticles are associated with venous thrombogenesis.  Academic Article
• P-selectin knockout: a mouse model for various human diseases.  Academic Article
• P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.  Academic Article
• P-selectin promotes neutrophil extracellular trap formation in mice.  Academic Article
• P-selectin, a granule membrane protein of platelets and endothelial cells, follows the regulated secretory pathway in AtT-20 cells.  Academic Article
• PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells.  Academic Article
• PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes.  Academic Article
• PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15).  Academic Article
• PSGL-1 regulates platelet P-selectin-mediated endothelial activation and shedding of P-selectin from activated platelets.  Academic Article
• Platelet P-selectin facilitates atherosclerotic lesion development.  Academic Article
• Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice.  Academic Article
• Platelet granule secretion continuously prevents intratumor hemorrhage.  Academic Article
• Platelet-endothelial interactions in inflamed mesenteric venules.  Academic Article
• Platelet-mediated lymphocyte delivery to high endothelial venules.  Academic Article
• Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin.  Academic Article
• Pro-coagulant state resulting from high levels of soluble P-selectin in blood.  Academic Article
• Prominent role of P-selectin in the development of advanced atherosclerosis in ApoE-deficient mice.  Academic Article
• Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice.  Academic Article
• Remodeling of the lectin-EGF-like domain interface in P- and L-selectin increases adhesiveness and shear resistance under hydrodynamic force.  Academic Article
• Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses.  Academic Article
• Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin.  Academic Article
• Selectin receptor-ligand bonds: Formation limited by shear rate and dissociation governed by the Bell model.  Academic Article
• Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins.  Academic Article
• The A2B adenosine receptor protects against inflammation and excessive vascular adhesion.  Academic Article
• The P-selectin, tissue factor, coagulation triad.  Academic Article
• The Weibel-Palade body: the storage granule for von Willebrand factor and P-selectin.  Academic Article
• The combined role of P- and E-selectins in atherosclerosis.  Academic Article
• The kinetics and shear threshold of transient and rolling interactions of L-selectin with its ligand on leukocytes.  Academic Article
• The kinetics of L-selectin tethers and the mechanics of selectin-mediated rolling.  Academic Article
• Tissue factor expressed by circulating cancer cell-derived microparticles drastically increases the incidence of deep vein thrombosis in mice.  Academic Article
• Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm.  Academic Article
• Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo.  Academic Article