Dynactin Complex
Concept
Overview
subject area of
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A novel action of histone deacetylase inhibitors in a protein aggresome disease model. Academic Article
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A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization. Academic Article
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A role for cytoplasmic dynein and LIS1 in directed cell movement. Academic Article
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Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes. Academic Article
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Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3. Academic Article
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BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Academic Article
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Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo. Academic Article
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Disease-associated mutations in human BICD2 hyperactivate motility of dynein-dynactin. Academic Article
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Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends. Academic Article
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EB1 targets to kinetochores with attached, polymerizing microtubules. Academic Article
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Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked. Academic Article
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Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix. Academic Article
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Interaction between EB1 and p150glued is required for anaphase astral microtubule elongation and stimulation of cytokinesis. Academic Article
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MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression. Academic Article
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Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells. Academic Article
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Molecular requirements for bi-directional movement of phagosomes along microtubules. Academic Article
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Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin. Academic Article
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Nuclear envelope: torn apart at mitosis. Academic Article
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Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3. Academic Article
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Rapid transport of neural intermediate filament protein. Academic Article
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Regional variation of microtubule flux reveals microtubule organization in the metaphase meiotic spindle. Academic Article
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Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin. Academic Article
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Regulators of the cytoplasmic dynein motor. Academic Article
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The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Academic Article
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The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. Academic Article
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The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1). Academic Article
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The product of the Drosophila gene, Glued, is the functional homologue of the p150Glued component of the vertebrate dynactin complex. Academic Article
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Tyrosination of ?-tubulin controls the initiation of processive dynein-dynactin motility. Academic Article
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lis-1 is required for dynein-dependent cell division processes in C. elegans embryos. Academic Article