subject area of
- APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. Academic Article
- ATP is required for the release of the anaphase-promoting complex/cyclosome from inhibition by the mitotic checkpoint. Academic Article
- Affinity purification of mitotic anaphase-promoting complex/cyclosome on p13Suc1. Academic Article
- Binding of activated cyclosome to p13(suc1). Use for affinity purification. Academic Article
- Cyclin-specific control of ribosomal DNA segregation. Academic Article
- Dual mode of degradation of Cdc25 A phosphatase. Academic Article
- Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes. Academic Article
- From rabbit reticulocytes to clam oocytes: in search of the system that targets mitotic cyclins for degradation. Academic Article
- Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint. Academic Article
- Limited functional redundancy and oscillation of cyclins in multinucleated Ashbya gossypii fungal cells. Academic Article
- Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events. Academic Article
- Mechanisms and regulation of the degradation of cyclin B. Academic Article
- Mode of interaction of TRIP13 AAA-ATPase with the Mad2-binding protein p31comet and with mitotic checkpoint complexes. Academic Article
- Mutual antagonism between the anaphase promoting complex and the spindle assembly checkpoint contributes to mitotic timing in Caenorhabditis elegans. Academic Article
- Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint. Academic Article
- Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20. Academic Article
- Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit. Academic Article
- Protein dynamics at the kinetochore: cell cycle regulation of the metaphase to anaphase transition. Academic Article
- Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells. Academic Article
- Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation. Academic Article
- Regulation of APC/C (Cdh1) ubiquitin ligase in differentiation of human embryonic stem cells. Academic Article
- Regulation of mRNA translation during mitosis. Academic Article
- Regulation of the action of early mitotic inhibitor 1 on the anaphase-promoting complex/cyclosome by cyclin-dependent kinases. Academic Article
- Regulatory modules: Coupling protein stability to phopshoregulation during cell division. Academic Article
- Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome. Academic Article
- Role of Suc1 in the activation of the cyclosome by protein kinase Cdk1/cyclin B. Academic Article
- Role of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint complex. Academic Article
- Roles of different pools of the mitotic checkpoint complex and the mechanisms of their disassembly. Academic Article
- Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding. Academic Article
- Roles of ubiquitin-mediated proteolysis in cell cycle control. Academic Article
- Spatiotemporal regulation of the anaphase-promoting complex in mitosis. Academic Article
- Systematic analysis of human protein complexes identifies chromosome segregation proteins. Academic Article
- The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome. Academic Article
- The Giardia cell cycle progresses independently of the anaphase-promoting complex. Academic Article
- The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication. Academic Article
- The anaphase-promoting complex/cyclosome is required for anaphase progression in multinucleated Ashbya gossypii cells. Academic Article
- The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk. Academic Article
- The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit. Academic Article
- The ubiquitin system for protein degradation and some of its roles in the control of the cell division cycle. Academic Article
- Transitions regulating the timing of cytokinesis in embryonic cells. Academic Article
- Two different mitotic checkpoint inhibitors of the anaphase-promoting complex/cyclosome antagonize the action of the activator Cdc20. Academic Article
- Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Academic Article
- p31comet Promotes disassembly of the mitotic checkpoint complex in an ATP-dependent process. Academic Article