Publications in VIVO

Co-author Network

Hammarlund, Marc Whitman Center Scientist, Whitman Center

Positions

Associate Professor, Department of Genetics, Yale New Haven Hospital 2015 -
Whitman Center Scientist, Whitman Center, Marine Biological Laboratory 2016 -

Marc did his doctoral work with Erik Jorgensen, studying genetics and synaptic transmission. In his postdoc with Mike Bastiani he pioneered the study of axon regeneration in C. elegans and discovered the DLK regeneration pathway. The Hammarlund lab develops novel ways to study the cell biology of neurons in vivo. We study how neurons prevent degeneration, repair injury, and maintain circuit function.

Publications
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selected publications

academic article
- Axon regeneration in C. elegans: Worming our way to mechanisms of axon regeneration.. Experimental Neurology. 287:300-309. 2017
- Mitochondria Localize to Injured Axons to Support Regeneration.. Neuron. 92:1308-1323. 2016
- Inhibition of Poly-ADP-Ribosylation Fails to Increase Axonal Regeneration or Improve Functional Recovery after Adult Mammalian CNS Injury.. eNeuro. 3:ENEURO.0270-16.2016-ENEURO.0270-16.2016. 2016
- Inhibiting poly(ADP-ribosylation) improves axon regeneration.. Elife. 5. 2016
- RNA ligation in neurons by RtcB inhibits axon regeneration.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 112:8451-8456. 2015
- A multi-channel device for high-density target-selective stimulation and long-term monitoring of cells and subcellular features in C. elegans.. Lab on a Chip. 14:4513-4522. 2014
- The RtcB RNA ligase is an essential component of the metazoan unfolded protein response.. EMBO Reports. 15:1278-1285. 2014
- Axon regeneration in C. elegans.. Curr Opin Neurobiol. 27:199-207. 2014
- Syndecan promotes axon regeneration by stabilizing growth cone migration.. Cell Rep. 8:272-283. 2014
- Bidirectional thermotaxis in Caenorhabditis elegans is mediated by distinct sensorimotor strategies driven by the AFD thermosensory neurons.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 111:2776-2781. 2014
- Insulin/IGF1 signaling inhibits age-dependent axon regeneration.. Neuron. 81:561-573. 2014
- Axon regeneration genes identified by RNAi screening in C. elegans.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:629-645. 2014
- Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans.. PloS one. 9:e114459. 2014
- Neuron-specific feeding RNAi in C. elegans and its use in a screen for essential genes required for GABA neuron function.. PLoS genetics. 9:e1003921. 2013
- Rapid and permanent neuronal inactivation in vivo via subcellular generation of reactive oxygen with the use of KillerRed.. Cell Rep. 5:553-563. 2013
- Science in Suzhou: establishment and function of neural circuits.. EMBO Reports. 13:286-288. 2012
- Notch signaling inhibits axon regeneration.. Neuron. 73:268-278. 2012
- Neural regeneration in Caenorhabditis elegans.. Annual Review of Genetics. 46:499-513. 2012
- In vivo laser axotomy in C. elegans.. J Vis Exp. 2011
- Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 107:22399-22406. 2010
- Axon regeneration requires a conserved MAP kinase pathway.. Science Science. 323:802-806. 2009
- CAPS and syntaxin dock dense core vesicles to the plasma membrane in neurons.. Journal of Cell Biology. 180:483-491. 2008
- Open syntaxin docks synaptic vesicles.. PLoS biology. 5:e198. 2007
- Axons break in animals lacking beta-spectrin.. Journal of Cell Biology. 176:269-275. 2007
- Single-nucleotide polymorphism mapping.. Methods in molecular biology (Clifton, N.J.). 351:75-92. 2006
- Heterozygous insertions alter crossover distribution but allow crossover interference in Caenorhabditis elegans.. Genetics. 171:1047-1056. 2005
- Rapid single nucleotide polymorphism mapping in C. elegans.. BMC Genomics. 6:118. 2005
- Mutations in beta-spectrin disrupt axon outgrowth and sarcomere structure.. Journal of Cell Biology. 149:931-942. 2000
conference paper
- Poly(ADP-Ribosylation) Regulates Axon Regeneration.. Molecular Biology of the Cell.