Self-organization of polymer-motor systems in the cytoskeleton. Academic Article uri icon


  • Microtubules and actin filaments are organized into dynamic arrays inside cells. In this paper I discuss in conceptual form the assembly mechanisms of three specific arrays: asters, spindles and leading edge structures. The role of energy transducing processes, particularly motor protein activity, in assembly is explored. I conclude that dynamic interaction between motor proteins and cytoskeletal polymers play a very general role in spatial organization of the cytoplasm.

publication date

  • April 29, 1992