Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse. Academic Article uri icon

abstract

  • The relationship between calcium current and transmitter release was studied in squid giant synapse. It was found that the voltage-dependent calcium current triggers the release of synaptic transmitter in direct proportion to its magnitude and duration. Transmitter release occurs with a delay of approximately 200 mus after the influx of calcium. A model is presented which describes these relations formally.

publication date

  • March 1981