Spindle positioning: actin mediates pushing and pulling. Academic Article uri icon


  • To divide asymmetrically, the mitotic spindle is moved from the cell center to the cortex, a process that requires astral microtubules and the microtubule-based motor dynein. New work examining spindle positioning in large oocytes shows that in these cells actin and actin polymerization plays a key role.

publication date

  • February 24, 2009