MRCK-related compositions and methods Academic Article uri icon

abstract

  • This invention provides a composition comprising a pharmaceutically acceptable carrier and a nucleic acid which, when introduced into a cell wherein MRCK is expressed, inhibits the expression of MRCK in the cell. This invention further provides a method for identifying an agent that inhibits MRCK expression in a cell. This invention further provides a method for identifying an agent that inhibits MRCK-mediated kinase activity in a cell. This invention further provides a method for inhibiting the MRCK-mediated migration of a cell in a subject. Finally, this invention provides related methods of treating a subject.

publication date

  • April 18, 2006