Synaptotagmin: fusogenic role for calcium sensor? Academic Article uri icon

abstract

  • Two recent studies focusing on synaptotagmin-1’ s role in synaptic vesicle fusion suggest that it may be key in bringing vesicle and target membranes together and in promoting SNARE assembly. The highly positive electrostatic potential of the synaptotagmin surface could catalyze fusion.

publication date

  • April 2006