ER biogenesis: self-assembly of tubular topology by protein hairpins. Academic Article uri icon

abstract

  • The structure of the endoplasmic reticulum (ER) depends on members of the reticulon and DP1/Yop1p families. Two of these proteins are sufficient to form tubular membrane networks from pure phospholipid vesicles, thus revealing a new paradigm of ER morphogenesis.

publication date

  • June 3, 2008