abstract

• Centromeres are epigenetically defined chromatin domains marked by the presence of the histone H3 variant CENP-A. Here we review recent structural and biochemical work on CENP-A, and advances in understanding the mechanisms that propagate and read centromeric chromatin domains.

authors

• Maddox, Paul
• [Corbett, Kevin D]
• [Desai, A]

status

• published 

publication date

• April 2012

has subject area

• 0604 Genetics
• Animals
• Autoantigens
• Centromere
• Centromere Protein A
• Chromatin
• Chromosomal Proteins, Non-Histone
• Developmental Biology
• Humans
• Protein Binding

published in

• Current Opinion in Genetics & Development  Journal

keywords

• Animals
• Autoantigens
• Centromere
• Centromere Protein A
• Chromatin
• Chromosomal Proteins, Non-Histone
• Humans
• Protein Binding

Digital Object Identifier (DOI)

• 10.1016/j.gde.2011.11.005

start page

• 139

end page

• 147

volume

• 22

issue

• 2