selected publications
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academic article
- Activation of autophagy rescues synaptic and cognitive deficits in fragile X mice.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 115:E9707-E9716. 2018
- Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die.. Cell Death & Differentiation. 24:317-329. 2017
- Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 113:E6290-E6297. 2016
- Estradiol pretreatment ameliorates impaired synaptic plasticity at synapses of insulted CA1 neurons after transient global ischemia.. Brain Research. 1621:222-230. 2015
- Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 110:4738-4743. 2013
- Mouse Transient Global Ischemia Two-Vessel Occlusion Model.. Bio Protoc. 2. 2012
- Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal death.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 109:E962-E971. 2012
- N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death.. Nature Neuroscience. 15:574-580. 2012
- EphB controls NMDA receptor function and synaptic targeting in a subunit-specific manner.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31:5353-5364. 2011
- Differences in NMDA receptor expression during human development determine the response of neurons to HIV-tat-mediated neurotoxicity.. Neurotoxicity Research. 19:138-148. 2011
- Caveolin-1 knockout mice exhibit impaired induction of mGluR-dependent long-term depression at CA3-CA1 synapses.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 107:21778-21783. 2010
- Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 107:3204-3209. 2010
- SNAP-25 is a target of protein kinase C phosphorylation critical to NMDA receptor trafficking.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30:242-254. 2010
- Regulation of NMDA receptor Ca2+ signalling and synaptic plasticity.. Biochemical Society transactions. 37:1369-1374. 2009
- Developmental switch in requirement for PKA RIIbeta in NMDA-receptor-dependent synaptic plasticity at Schaffer collateral to CA1 pyramidal cell synapses.. Neuropharmacology. 56:56-65. 2009
- Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 105:4892-4897. 2008
- Ischemic insults promote epigenetic reprogramming of mu opioid receptor expression in hippocampal neurons.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 104:4170-4175. 2007
- HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 104:3438-3443. 2007
- PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 103:19902-19907. 2006
- Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26:6851-6862. 2006
- Protein kinase A regulates calcium permeability of NMDA receptors.. Nature Neuroscience. 9:501-510. 2006
- Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 102:12230-12235. 2005
- Postsynaptic density protein-95 regulates NMDA channel gating and surface expression.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24:10138-10148. 2004
- Late calcium EDTA rescues hippocampal CA1 neurons from global ischemia-induced death.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24:9903-9913. 2004
- Ischemic preconditioning: neuronal survival in the face of caspase-3 activation.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24:2750-2759. 2004
- Electrical coupling and neuronal synchronization in the Mammalian brain.. Neuron. 41:495-511. 2004
- Ischemic insults derepress the gene silencer REST in neurons destined to die.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23:2112-2121. 2003
- Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 100:2906-2910. 2003
- Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22:2115-2124. 2002
- Ischemic preconditioning acts upstream of GluR2 down-regulation to afford neuroprotection in the hippocampal CA1.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 99:2362-2367. 2002
- Global ischemia-induced increases in the gap junctional proteins connexin 32 (Cx32) and Cx36 in hippocampus and enhanced vulnerability of Cx32 knock-out mice.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21:7534-7542. 2001
- Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21:6058-6068. 2001
- mGluR1-mediated potentiation of NMDA receptors involves a rise in intracellular calcium and activation of protein kinase C.. Neuropharmacology. 40:856-865. 2001
- Protein kinase C modulates NMDA receptor trafficking and gating.. Nature Neuroscience. 4:382-390. 2001
- Insulin promotes rapid delivery of N-methyl-D- aspartate receptors to the cell surface by exocytosis.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 98:3561-3566. 2001
- The AMPAR subunit GluR2: still front and center-stage.. Brain Research. 886:190-207. 2000
- Remodeling of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit composition in hippocampal neurons after global ischemia.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 97:13360-13365. 2000
- Status epilepticus decreases glutamate receptor 2 mRNA and protein expression in hippocampal pyramidal cells before neuronal death.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 97:3631-3636. 2000
- Patterns of developmental expression of the RNA editing enzyme rADAR2.. Neuroscience. 95:869-879. 2000
- Protein kinase C potentiation of N-methyl-D-aspartate receptor activity is not mediated by phosphorylation of N-methyl-D-aspartate receptor subunits.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 96:15262-15267. 1999
- Knockdown of AMPA receptor GluR2 expression causes delayed neurodegeneration and increases damage by sublethal ischemia in hippocampal CA1 and CA3 neurons.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19:9218-9227. 1999
- Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels.. Biophysical Journal. 76:2899-2911. 1999
- Mutation of structural determinants lining the N-methyl-D-aspartate receptor channel differentially affects phencyclidine block and spermine potentiation and block.. Neuroscience. 93:125-134. 1999
- Aurintricarboxylic acid prevents GLUR2 mRNA down-regulation and delayed neurodegeneration in hippocampal CA1 neurons of gerbil after global ischemia.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 95:7115-7120. 1998
- Reply - To comment letter by Ben-Ari (The GluR2 Hypothesis..). Trends in Neurosciences. 21:242-242. 1998
- Ca2+ influx amplifies protein kinase C potentiation of recombinant NMDA receptors.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17:8676-8686. 1997
- Status epilepticus-induced alterations in metabotropic glutamate receptor expression in young and adult rats.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17:8588-8595. 1997
- The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders.. Trends in Neurosciences. 20:464-470. 1997
- Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17:6179-6188. 1997
- Developmental regulation of glutamate and GABA(A) receptor gene expression in rat hippocampus following kainate-induced status epilepticus.. Developmental neuroscience. 19:529-542. 1997
- The GluR2 hypothesis: Ca(++)-permeable AMPA receptors in delayed neurodegeneration.. Cold Spring Harb Symp Quant Biol. 61:373-384. 1996
- Alternatively spliced isoforms of the NMDARI receptor subunit.. Trends in Neurosciences. 18:306-313. 1995
- Spermine potentiation of recombinant N-methyl-D-aspartate receptors is affected by subunit composition.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 91:10883-10887. 1994
- AMPA/kainate receptor gene expression in normal and Alzheimer's disease hippocampus.. Neuroscience. 61:41-49. 1994
- Kainate-induced status epilepticus alters glutamate and GABAA receptor gene expression in adult rat hippocampus: an in situ hybridization study. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14:2697-2707. 1994
- Kainate-induced status epilepticus alters glutamate and GABAA receptor gene expression in adult rat hippocampus: an in situ hybridization study.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14:2697-2707. 1994
- Mutagenesis rescues spermine and Zn2+ potentiation of recombinant NMDA receptors.. Neuron. 12:811-818. 1994
- Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 90:6731-6735. 1993
- Effects of polyamines on NMDA-induced currents in rat hippocampal neurons: a whole-cell and single-channel study.. Neurosci Lett. 152:107-112. 1993
- Molecular biology of PCP and NMDA receptors.. NIDA Res Monogr. 133:159-183. 1993
- Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 89:10499-10503. 1992
- Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 89:9359-9363. 1992
- Are Ca(2+)-permeable kainate/AMPA receptors more abundant in immature brain?. Neurosci Lett. 144:65-69. 1992
- Differential expression of three glutamate receptor genes in developing rat brain: an in situ hybridization study.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 88:4157-4161. 1991
- Interaction of Mg2+ and phencyclidine in use-dependent block of NMDA channels.. Neurosci Lett. 123:187-191. 1991
- Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in xenopus oocytes.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 87:9971-9974. 1990
- Glycine decreases desensitization of N-methyl-D-aspartate (NMDA) receptors expressed in Xenopus oocytes and is required for NMDA responses.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 87:2354-2358. 1990
- N-methyl-D-aspartate activates different channels than do kainate and quisqualate.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 86:2083-2087. 1989
- mRNA from NCB-20 cells encodes the N-methyl-D-aspartate/phencyclidine receptor: a Xenopus oocyte expression study.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 86:1708-1711. 1989
- mRNA from NCB-20 cells encodes the N-methyl-D-aspartate/phencyclidine receptor: a Xenopus oocyte expression study.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 86:1708-1711. 1989
- Coexpression of N-methyl-D-aspartate and phencyclidine receptors in Xenopus oocytes injected with rat brain mRNA.. Proceedings of the National Academy of Sciences Proceedings of the National Academy of Sciences. 85:3250-3254. 1988
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conference paper
- Mitochondria and Memory: Bioenergetics, Synaptic Plasticity and Neurodegeneration. Biophysical Journal. 180a-180a. 2017