academic article

• Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing..  Nature Genetics.  51:414-430. 2019
• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease..  Nature Genetics.  49:1373-1384. 2017
• Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans..  Alzheimer's & Dementia.  13:119-129. 2017
• Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk..  Alzheimer's & Dementia.  12:233-243. 2016
• A novel Alzheimer disease locus located near the gene encoding tau protein..  Molecular Psychiatry.  21:108-117. 2016
• Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals..  JAMA Neurol.  72:1313-1323. 2015
• Rarity of the Alzheimer disease-protective APP A673T variant in the United States..  JAMA Neurol.  72:209-216. 2015
• Synaptic, transcriptional and chromatin genes disrupted in autism..  Nature Nature.  515:209-215. 2014
• Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study..  JAMA Neurol.  71:1394-1404. 2014
• A framework for the interpretation of de novo mutation in human disease..  Nature Genetics.  46:944-950. 2014
• Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias..  PLoS genetics.  10:e1004606. 2014
• PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation..  Annals of Neurology.  76:379-392. 2014
• Convergence of genes and cellular pathways dysregulated in autism spectrum disorders..  American Journal of Human Genetics.  94:677-694. 2014
• Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease..  PloS one.  9:e94661. 2014
• Whole exome sequencing reveals minimal differences between cell line and whole blood derived DNA..  Genomics.  102:270-277. 2013
• Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs..  Nature Genetics.  45:984-994. 2013
• Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans..  JAMA : the journal of the American Medical Association.  309:1483-1492. 2013
• Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls..  PLoS genetics.  9:e1003443. 2013
• Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders..  Neuron.  77:235-242. 2013
• Integrated model of de novo and inherited genetic variants yields greater power to identify risk genes..  PLoS genetics.  9:e1003671. 2013
• Individual common variants exert weak effects on the risk for autism spectrum disorders..  Human Molecular Genetics.  21:4781-4792. 2012
• Patterns and rates of exonic de novo mutations in autism spectrum disorders..  Nature Nature.  485:242-245. 2012
• A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder..  Human Genetics.  131:565-579. 2012
• Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease..  Nature Genetics.  43:436-441. 2011
• Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes..  Archives of Neurology -Chigago-.  67:1473-1484. 2010
• A genome-wide scan for common alleles affecting risk for autism..  Human Molecular Genetics.  19:4072-4082. 2010
• High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility..  Molecular Psychiatry.  15:954-968. 2010
• Functional impact of global rare copy number variation in autism spectrum disorders..  Nature Nature.  466:368-372. 2010
• Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes..  PLoS genetics.  5:e1000536. 2009
• Autism genome-wide copy number variation reveals ubiquitin and neuronal genes..  Nature Nature.  459:569-573. 2009
• Common genetic variants on 5p14.1 associate with autism spectrum disorders..  Nature Nature.  459:528-533. 2009
• Mapping autism risk loci using genetic linkage and chromosomal rearrangements..  Nature Genetics.  39:319-328. 2007