academic article

• Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing..  Nature Genetics.  51:414-430. 2019
• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease..  Nature Genetics.  49:1373-1384. 2017
• A novel Alzheimer disease locus located near the gene encoding tau protein..  Molecular Psychiatry.  21:108-117. 2016
• Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease..  PloS one.  9:e94661. 2014
• Aberrant neurite outgrowth by HIV-gp120 is mediated via activation of Cdk5.  Journal of NeuroVirology.  18:59-60. 2012
• Overexpression of p35 in Min6 pancreatic beta cells induces a stressed neuron-like apoptosis..  Journal of the Neurological Sciences.  299:101-107. 2010
• Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  30:8457-8467. 2010
• Neurofilament tail phosphorylation: identity of the RT-97 phosphoepitope and regulation in neurons by cross-talk among proline-directed kinases..  Journal of Neurochemistry.  107:35-49. 2008
• Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons..  Molecular Biology of the Cell.  18:3645-3655. 2007
• Peptides derived from Cdk5 activator p35, specifically inhibit deregulated activity of Cdk5..  Biotechnology Journal.  2:978-987. 2007
• Cdk5 Modulation of mitogen-activated protein kinase signaling regulates neuronal survival..  Molecular Biology of the Cell.  18:404-413. 2007
• Inhibition of Cdk5 Sustains Mapk (Erk1/2) Activation in Cortical Neurons and Induces Apoptosis.  Molecular Biology of the Cell.  17. 2006
• Neuronal nuclear organization is controlled by cyclin-dependent kinase 5 phosphorylation of Ras Guanine nucleotide releasing factor-1..  Neuro-Signals Biological signals and receptors.  15:157-173. 2006
• A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons..  EMBO Journal.  24:209-220. 2005
• Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease..  American Journal of Pathology.  165:795-805. 2004
• p35/cyclin-dependent kinase 5 phosphorylation of ras guanine nucleotide releasing factor 2 (RasGRF2) mediates Rac-dependent Extracellular Signal-regulated kinase 1/2 activity, altering RasGRF2 and microtubule-associated protein 1b distribution in neurons..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  24:4421-4431. 2004
• Neuronal cyclin-dependent kinase 5: role in nervous system function and its specific inhibition by the Cdk5 inhibitory peptide..  BBA - Protein Structure and Molecular Enzymology BBA - Proteins and Proteomics.  1697:143-153. 2004
• Cdk5 regulates axonal transport and phosphorylation of neurofilaments in cultured neurons..  Journal of cell science.  117:933-941. 2004
• p35/Cdk5 phosphorylates RasGRF2 regulating RasGRF2-mediated Rac signaling and ERK1/2 activity.  Journal of Neurochemistry.  88:81-81. 2004
• Phosphorylation Activity in the Alzheimer's Disease and Normal Brain is Modulated by Microtubule-Associated Protein, Tau in Vitro..  Journal of Alzheimer's disease : JAD.  1:169-182. 1999
• Alterations in the neurofilament cytoskeleton of dorsal root ganglia neurons consequent to microinjection of cdk5/p35.  Molecular Biology of the Cell.  8:1614-1614. 1997
• Phosphorylation of human high molecular weight neurofilament protein (hNF-H) by neuronal cyclin-dependent kinase 5 (cdk5)..  Brain Research.  765:259-266. 1997
• Inhibition of neuronal cyclin-dependent kinase-5 by staurosporine and purine analogs is independent of activation by Munc-18..  Neurochemical Research.  21:629-636. 1996
• A multimeric kinase-cytoskeletal complex associates with Munc-18/P67 in rat brain.  Journal of Neurochemistry.  66:S64-S64. 1996
• CHARACTERIZATION OF CYCLIN-DEPENDENT KINASE-5 FROM RAT-BRAIN.  Molecular Biology of the Cell.  6:1407-1407. 1995
• NEURONAL CYCLIN-DEPENDENT KINASE-5 IS INHIBITED BY STAUROSPORINE AND OLOMOUCINE.  Molecular Biology of the Cell.  6:1408-1408. 1995
• P13suc1 associates with a cdc2-like kinase in a multimeric cytoskeletal complex in squid axoplasm..  The Journal of neuroscience : the official journal of the Society for Neuroscience.  15:6222-6229. 1995