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Publications in VIVO

Shribak, Michael Associate Scientist, Bell Center


My research lies in the biomedical optics, and employs a combination of optical, mechanical and software designs to create advanced light microscopes for studying the architectural dynamics in living cells. In particular, we invented new types of polarized light and differential interference microscopes which non-invasively create contrast where structures are otherwise invisible. These new imaging modes allow us to observe and record living cells with extremely fine details, some of which have never been seen with any other mode of microscopy before. Since image contrast in these modes is generated without the need to stain or to modify the cell in any way, cells can be followed for long periods of time, non-invasively, as they undergo mitosis, organelle movement or transformation, morphogenesis, and other dynamic changes. Yet these imaging modes should be compatible with fluorescent staining if desired.

selected publications