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Publications in VIVO

Wilhelm, Jim HHMI/HCIA Summer Institute Principal Investigator, Whitman Center


One of the central questions in cell biology is how proteins are sorted to particular regions of the cell. While most of the focus in cell biology has been on how different membrane bound compartments are defined, relatively little is known about how the cytoplasm is organized. While the cytoplasm of the cell is often viewed as little more than a sea of enzymes, the complexity of the biochemical and signaling pathways within the cell argue that a high degree of organization is necessary to ensure that pathways are regulated correctly and don’t interfere with each other. Our long-term goal is to identify and characterize these novel mechanisms of intracellular organization and their role in human disease.

selected publications